- Chronic Placental Inflammation as a Risk Factor of Severe Retinopathy of Prematurity
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Chae Young Kim, Euiseok Jung, Eun Na Kim, Chong Jai Kim, Joo Yong Lee, Ji Hye Hwang, Woo Sun Song, Byong Sop Lee, Ellen Ai-Rhan Kim, Ki-Soo Kim
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J Pathol Transl Med. 2018;52(5):290-297. Published online July 16, 2018
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DOI: https://doi.org/10.4132/jptm.2018.07.09
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 Abstract
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- Background
Chronic placental inflammation (CPI) has been implicated in the pathogenesis of diseases in premature infants, whereas retinopathy of prematurity (ROP) is a major complication primarily affecting preterm and very low-birth-weight (VLBW) infants. This study aims to investigate the association between CPI and ROP in VLBW infants.
Methods
We performed a retrospective review of clinical records of VLBW infants born between 2013 and 2016. Placental pathology findings including CPI cases were analyzed using logistic regression to study infants’ morbidities and other clinical characteristics.
Results
A total of 402 infants with a mean (standard deviation) gestational age of 28.5 (2.8) weeks and birth weight of 1,027.2 (304.4) g were included. The incidence of ROP was 24.1%. CPI was found in 90 infants (22.4%), among which 28.9% (26 of 90) developed ROP, and 21.1% (19 of 90) underwent laser photocoagulation. Lower gestational age, lower birth weight, longer duration of oxygen supply, and presence of CPI were associated with the development of ROP. After adjustment for gestational age, birth weight, sex, duration of oxygen supply, and other overlapping placental pathology, CPI was associated with the odds for type 1 ROP that required laser photocoagulation (adjusted odds ratio, 2.739; 95% confidence interval, 1.112 to 6.749; p = .029).
Conclusions
CPI was associated with severe ROP requiring treatment with laser photocoagulation in VLBW infants.
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Citations
Citations to this article as recorded by  - Retinopathy prematurity: a systematic review and meta-analysis study based on neonatal and maternal risk factors
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The Journal of Maternal-Fetal & Neonatal Medicine.2024; 35(25): 8032. CrossRef - Retinopathy of prematurity and placental histopathology findings: A retrospective cohort study
Sam Ebenezer Athikarisamy, Geoffrey C. Lam, Matthew N. Cooper, Tobias Strunk
Frontiers in Pediatrics.2023;[Epub] CrossRef - Identification of clinical factors associated with timing and duration of spontaneous regression of retinopathy of prematurity not requiring treatment
Jamee Schoephoerster, Sydney Roston, Scott Lunos, Sara E. Ramel, Jill Anderson, Michael K. Georgieff, Ellen C. Ingolfsland
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Miaomiao Wang, Zhaoyu Wang, Yueyue Miao, Hongkui Wei, Jian Peng, Yuanfei Zhou
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CHILD`S HEALTH.2022; 17(3): 138. CrossRef - Development of the genomic inflammatory index (GII) to assess key maternal antecedents associated with placental inflammation
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Sarina M. Amin, Andres Gonzalez, Jade Guevara, Charlotte Bolch, Lorick Andersen, W. Clay Smith, Swati Agarwal-Sinha
Ophthalmic Research.2021; 64(1): 91. CrossRef - A pilot randomised clinical trial of 670 nm red light for reducing retinopathy of prematurity
Alison L. Kent, Mohamed E. Abdel-Latif, Timothy Cochrane, Margaret Broom, Jane E. Dahlstrom, Rohan W. Essex, Bruce Shadbolt, Riccardo Natoli
Pediatric Research.2020; 87(1): 131. CrossRef - Exercise prevents the adverse effects of maternal obesity on placental vascularization and fetal growth
Jun Seok Son, Xiangdong Liu, Qiyu Tian, Liang Zhao, Yanting Chen, Yun Hu, Song Ah Chae, Jeanene M. de Avila, Mei‐Jun Zhu, Min Du
The Journal of Physiology.2019; 597(13): 3333. CrossRef - Cumulative evidence for association of sepsis and retinopathy of prematurity
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